Theophylline

Theophylline is a drug, a PDE inhibitor, that is widely used in pharmacotherapy.

Theophylline is also known as 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione or 1,3-dimethylxanthine and the chemical formula is C₇H₈N₄O₂. It has molecular weight of 180.16. It is naturally found in tea.

The main actions of theophylline are :

• relaxation of bronchial smooth muscle
• positive inotropic effect
• positive chronotropic effect
• lowers blood pressure
• increases renal blood flow
• some anti-inflammatory effect

The main therapeutic uses of theophylline are :

• chronic obstructive diseases of the airways
  • COPD
  • bronchial asthma

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